作者：Zhong Luo, Kaiyong Cai, Yan Hu, Jinghua Li, Xingwei Ding, Beilu Zhang, Dawei Xu, Peng Liu
關(guān)鍵字：mesoporous silica
論文來(lái)源：期刊
具體來(lái)源：Advanced Materials, 2012, 24, 431–435
發(fā)表時(shí)間：2012年
A novel redox responsive controlleddrug release system based on magnetic nanoparticles for efficient intracellular anticancer drug delivery is fabricated. Disulfide bonds are employed as intermediate linkers to immobilize PEI/β-CD molecules as nanoreservoirs for drug loading onto magnetic nanoparticles. The endocytotic pathway and endosomal escape of the smart controlled drug release system is proposed.