私密直播全婐app免费大渔直播,国产av成人无码免费视频,男女同房做爰全过程高潮,国产精品自产拍在线观看

相關(guān)鏈接
聯(lián)系方式
  • 通信地址:陜西省西安市長安區(qū)西北工業(yè)大學(xué)化學(xué)與化工學(xué)院
  • 郵編:710129
  • 電話:13772401347
  • 傳真:
  • Email:happytw_3000@163.com
當(dāng)前位置:> 首頁 > 論文著作 > 正文
[Chem. Commun] Reversible morphology transitions of supramolecular polymer self-assemblies for switch-controlled drug release
作者:Haitao Zhang, Xiaodong Fan,* Rongtian Suo, Hui Li, Zhen Yang, Wanbin Zhang, Yang Bai, Hao Yao and We
關(guān)鍵字:the reversible morphology transitions,switch-controlled drug release
論文來源:期刊
具體來源:Chem. Commun.,2015,51, 15366-15369
發(fā)表時(shí)間:2015年

A novel method for switch-controlled drug release was developed through the reversible morphology transitions of supramolecular branched copolymer self-assemblies. The reversible transitions from vesicles to nanoparticles were successfully achieved by alternating UV and visible light irradiation to obtain morphology-controlled drug release in a switch mode.

In this study, we present a switch-controlled drug release system through light-triggered reversible morphology transitions of supramolecular self-assemblies from vesicles to nanoparticles on the basis of the destruction and reconstruction of a supramolecular branched copolymer (2(mPEG)-g-(PDEA-b-PEG-b-PDEA)-g-2(mPEG),
SBCP; Scheme 1a). SBCP was synthesized through the orthogonal self-assembly of poly((diethylamino)ethyl-methacrylate)-b-polyethyleneglycol- b poly((diethylamino)ethyl-methacrylate) containing two b-CD units at every terminal ((b-CD)2-g-(PDEA-b-PEG-b-PDEA)- g-(b-CD)2, P1) and methoxypolyethyleneglycols with single trans-Azo end-capping (mPEG-tAzo, P2). SBCP self-assembled into vesicles when the pH of the polymer solution was increased from 6.0 to 7.4. Doxycycline (DOX) molecules as a model drug were synchronously encapsulated into the vesicles (Scheme 1a and b). After alternating UV/visible light irradiation, the host–guest interactions between the b-CD and Azo groups in SBCP self-assemblies underwent reversible dissociation–association and led to the reversible morphology transitions from vesicles to nanoparticles (Scheme 1b–d and d–b) accompanied by the controlled release of DOX in an on–off switch mode.
全文鏈接:http://pubs.rsc.org/en/Content/ArticleLanding/2015/CC/C5CC05579B#!divAbstract

主站蜘蛛池模板: 于田县| 浦城县| 咸丰县| 莆田市| 广汉市| 东乡族自治县| 曲麻莱县| 中阳县| 梧州市| 富顺县| 黑水县| 中山市| 徐闻县| 和静县| 肃南| 襄垣县| 如皋市| 磐石市| 方山县| 金塔县| 礼泉县| 阳西县| 英山县| 太湖县| 密山市| 依兰县| 麻阳| 嘉黎县| 岳池县| 大足县| 平度市| 和林格尔县| 莱芜市| 锡林浩特市| 额尔古纳市| 甘泉县| 阳高县| 惠水县| 鄱阳县| 达尔| 封丘县|