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個人簡介

     史向陽,1970年8月生,化學化工與生物工程學院,生物科學與技術(shù)研究所教授,博士生導師,校特聘教授,上海高校特聘教授(東方學者)。2008年回國前,在美國密歇根大學歷任博士后研究員、第II級副研究員、研究員和研究助理教授。美國化學會、Sigma Xi 學會、中國化學會、中國生物材料委員會會員,是美國密歇根大學醫(yī)學和生物科學納米技術(shù)研究所客座研究員,首屆葡萄牙馬德拉大學“邀請納米技術(shù)主任(Invited Chair in Nanotechnology)。是Nat. Nanotechnol.和 J. Am. Chem. Soc.等64個國際雜志審稿人。主要從事納米醫(yī)學、環(huán)境納米技術(shù)、納米化學和納米材料合成及其應用研究。已申請發(fā)明專利21項,參加編寫6篇書的章節(jié),發(fā)表論文120多篇(SCI檢索90多篇)。

 

 教育:

 

1988/9-1992/7       理學學士      河南師范大學         化學
1992/9-1995/4       工學碩士      北京理工大學         應用化學
1995/9-1998/7       理學博士      中科院感光化學研究所         有機化學
 

 

工作經(jīng)歷:

 
1998/9-2000/5          博士后          清華大學
2000/5-2001/5         博士后          德國馬克斯-普朗克膠體與界面研究所
2001/5-2002/5        訪問學者       美國加州州立大學洛杉磯分校
2002/5-2003/5        博士后           美國密歇根大學安娜堡分校
2003/5-2005/5        第II級副研究員          美國密歇根大學安娜堡分校
2005/6-2008/4        研究員           美國密歇根大學安娜堡分校
2008/5-2008/8        研究助理教授          美國密歇根大學安娜堡分校
2008/6-至今            校特聘教授          東華大學
2008/6-至今           上海高校特聘教授(東方學者)          東華大學
2010/11-至今         邀請納米技術(shù)主任          葡萄牙馬德拉大學 (兼職)
 

 

獲獎:

    
1.      2000年,獲得德國馬普獎學金;
2.      2008年,獲得上海高校特聘教授(東方學者)稱號;
3.      2009年入圍首批SCOPUS尋找未來科學之星活動納米科學前10名;
4.       2010年入選首屆葡萄牙馬德拉大學納米技術(shù)邀請主任(Invited Chair in Nanotechnology at University of Madeira (UMa)/Centro de Química da Madeira (CQM), Supported by FCT-UMa/Santander Bank.

 

 

學術(shù)兼職:

 
 
1.      美國化學會、Sigma Xi 學會會員,中國化學會、中國生物材料委員會會員;
2.      美國密歇根大學醫(yī)學和生物科學納米技術(shù)研究所客座研究員;
3.      葡萄牙馬德拉大學化學系邀請納米技術(shù)主任(Invited Chair in Nanotechnology);
4.      Journal of Modern Textile Science and Engineering, 中國組織工程研究與臨床康復編委;
5.      Nature Nanotechnology, Journal of the American Chemical Society, Nano Letters, Chemical Communications, Biomacromolecules, Journal of Materials Chemistry, Lab on a Chip, Journal of Physical Chemistry B, Molecular Biosystems, Green Chemistry, Langmuir, Analyst, Nanotechnology, Dalton Transactions, Soft Matter, Physical Chemistry Chemical Physics, Bioorganic & Medicinal Chemistry, CrystEngComm, European Journal of Inorganic Chemistry, Colloids and Surfaces A: Physicochemical Engineering Aspects, Journal of Optics A: Pure and Applied Optics, Polymer Bulletin, Journal of Physics: Condensed Matter, Molecules, Journal of Nanoscience and Nanotechnology, Acta BiomaterialiaJournal of Environmental MonitoringOrganic & Biomolecular Chemistry, Journal of Physics D: Applied PhysicsIEEE Engineering in Medicine and Biology MagazineNew Journal of Chemistry, Nanotechnology, Science and Applications 56個國際專業(yè)雜志的審稿人;
6.      國家自然科學基金、教育部博士點基金和霍英東青年教師基金評審人,新加坡國立大學校基金項目評審人,美國Cottrell College Science Award proposal from Research Corporation for Science Advancement基金評審人,加拿大Alberta Nanotechnology Industrial Research Partnership Program 評審人,上海市科委重點項目評審人;
7.       200614屆復合物和納米工程國際會議生物復合材料分會主席,2009BIT Life Sciences’ 2nd Annual Congress and Expo of Molecular Diagnostics (CEMD-2009) 分會主席,20106th IUPAC International Symposium on Novel Materials and Their Synthesis (NMS-VI) and 20th International Symposium on Fine Chemistry and Functional Polymers (FCFP-XX)分會主席。
 

代表性著作:

 

1.      Wen Jin, Xiangyang Shi, Frank Caruso. High Activity Enzyme Microcrystal Multilayer Films.J. Am. Chem. Soc. 2001,123, 8121-8122.
2.      Frank Caruso,Xiangyang Shi, Rachel A. Caruso, Andrei Susha. Hollow Titania Spheres from Layered Precursor Deposition on Sacrificial Colloidal Core Particles. Advanced Materials 2001, 13, 740-744.
3.      Xiangyang Shi,* Wanyun Ma, Caomin Sun, Shikang Wu. The aggregation behavior of collagen in aqueous solution and its property of stabilizing liposomes in vitro. Biomaterials 2001, 22 (12): 1627-1634.
4.      Xiangyang Shi, Shubo Han, Raymond J. Sanedrin, Cesar Galvez, David G. Ho, Billy Hernandez, Feimeng Zhou, Matthias Selke. Formation of Cobalt Oxide Nanotubes: Effect of Intermolecular Hydrogen Bonding Between Co(III) Complex Precursors Incorporated onto Colloidal Templates. Nano Lett. 2002, 2, 289-293.
5.      Xiangyang Shi, Shubo Han, Raymond J. Sanedrin, Feimeng Zhou, Matthias Selke. Synthesis of Cobalt Oxide Nanotubes from Colloidal Particles Modified with a Co(III)-Cysteinato Precursor. Chem. Mater. 2002, 14, 1897-1902.
6.      Shubo Han, Xiangyang Shi, Feimeng Zhou. Polyelectrolyte Hollow Sphere Lithographic Patterning of Surfaces: Construction of 2-Dimensional Well-Ordered Metal Arrays. Nano Lett. 2002, 2, 97-100.
7.      Xiangyang Shi,* Mingwu Shen, Helmuth Moehwald. Polyelectrolyte multilayer nanoreactors toward the synthesis of diverse nanostructured materials. Invited review. Prog. Polym. Sci. 2004, 29, 987-1019.
8.      Mohammad T. Islam, Xiangyang Shi, Lajos P. Balogh, James R. Baker jr. HPLC separation of different generations of poly(amidoamine) (PAMAM) dendrimers modified with various terminal groups. Anal. Chem. 2005, 77, 2063-2070
9.      Xiangyang Shi, Istvan J. Majoros, James R. Baker Jr. Capillary Electrophoresis of Poly(amidoamine) Dendrimers: From Simple Derivatives to Complex Multi-functional Medical Nanodevices.Invited review. Mol. Pharmaceutics 2005, 2, 278-294.
10.   Wojciech Lesniak, Anna Bielinska, Kai Sun, Katarzyna Janczak, Xiangyang Shi, James R. Baker, Jr., Lajos Balogh. Silver/Dendrimer Nanocomposites as Biomarkers: Fabrication,Characterization, In Vitro Toxicity and Intracellular Detection. Nano Lett. 2005, 5, 2123-2130.
11.   Xiangyang Shi, István J. Majoros, Anil K. Patri, Xiangdong Bi, Mohammad T. Islam, Ankur Desai, T. Rose Ganser, James R. Baker, Jr. Molecular heterogeneity analysis of poly(amidoamine) dendrimer-based mono- and multifunctional nanodevices by capillary electrophoresis. Analyst 2006, 131, 374-381.
12.   Xiangyang Shi, Suhe Wang, Xisui Chen, Sasha Meshinchi, James R. Baker Jr. Encapsulation of Submicrometer-Sized 2-Methoxyestradiol Crystals into Polymer Multilayer Capsules for Biological Applications. Mol. Pharmaceutics 2006, 3, 144-151.
13.   Xiangyang Shi, Kai Sun, Lajos Balogh, James R. Baker, Jr. Synthesis, Characterization, and Manipulation of Dendrimer-Stabilized Iron Sulfide Nanoparticles. Nanotechnology 2006, 17, 4554-4560
14.   Xiangyang Shi,* Suhe Wang, Haiping Sun, James R. Baker Jr.* Improved Biocompatibility of Dendrimer-Entrapped Gold Nanoparticles. Soft Matter 2007, 3, 71-74
15.   Xiangyang Shi,* Suhe Wang,*Sasha Meshinchi,Mary E. Van Antwerp,Xiangdong Bi, Inhan Lee,James R. Baker, Jr*.Dendrimer-Entrapped Gold Nanoparticles as a Nanoplatform for Cancer-Cell Targeting and Imaging. Small 2007, 3, 1245-1252.
16.   Su He Wang*, Xiangyang Shi*, Mary Van Antwerp, Zhengyi Cao,Scott D. Swanson, Xiangdong Bi, James R. Baker, Jr.* Dendrimer-Functionalized Iron Oxide Nanoparticles for Specific Targeting and Imaging of Cancer Cells. Adv. Funct. Mater.2007, 17, 3403-3050.
17.   Xiangyang Shi*, Inhan Lee, James R. Baker, Jr*. Acetylation of dendrimer-entrapped gold and silver nanoparticles. J. Mater. Chem. 2008, 18, 586-593.
18.   Xiangyang Shi*, Su He Wang*, Scott D. Swanson,Song Ge, Zhengyi Cao, Mary Van Antwerp, Kevin J Landmark, James R. Baker, Jr*. Dendrimer-functionalized shell-crosslinked iron oxide nanoparticles for in vivo magnetic resonance imaging of tumors. Adv. Mater., 2008, 20, 1671-1678.
19.   Xiangyang Shi, Kai Sun, and James R. Baker, Jr. Spontaneous Formation of Functionalized Dendrimer-Stabilized Gold Nanoparticles. J. Phys. Chem. C. 2008, 112, 8251-8258.
20.   Mingwu Shen, Su He Wang, Xiangyang Shi, Xisui Chen, Qingguo Huang, Elijah J. Petersen, Roger A. Pinto, James R. Baker, Jr., and Walter J. Weber, Jr. Polyethyleneimine-Mediated Functionalization of Multi-Walled Carbon Nanotubes: Synthesis, Characterization, and in vitro Toxicity Assay. J. Phys. Chem. C 2009, 113(8), 3150-3156.
21.   Xiangyang Shi*, Su He Wang, Mingwu Shen, Mary E. Antwerp, Xisui Chen, Chang Li, Elijah J. Petersen, Qingguo Huang, Walter J. Weber, Jr., and James R. Baker, Jr. Multifunctional Dendrimer-Modified Multi-Walled Carbon Nanotubes: Synthesis, Characterization, and in vitro Cancer Cell Targeting and Imaging. Biomacromolecules 2009, 10, 1744-1750.
22.   Seungpyo Hong, Rahul Rattan, István J. Majoros, Douglas G. Mullen, Jennifer L. Peters, Xiangyang Shi, Ania Bielinska, Luz Blanco, Bradford G. Orr, James R. Baker, Jr., and Mark M. Banaszak Holl*. Exploring Membrane Porosity and Cellular Internalization Mechanisms of Poly(amidoamine) Dendrimers:  the Role of Sphingolipid GM1. Bioconjugate Chem. 2009, 20(8), 1503-1513
23.   Shili Xiao, Mingwu Shen, Rui Guo, Shanyuan Wang, and Xiangyang Shi*. Immobilization of Zero-Valent Iron Nanoparticles into Electrospun Polymer Nanofibers: Synthesis, Characterization, and Potential Environmental Applications. J. Phys. Chem. C 2009, 113, 18062-18068
24.   Rui Guo, Han Wang, Chen Peng, Mingwu Shen, Minjie Pan, Xueyan Cao, Guixiang Zhang*, Xiangyang Shi*. X-Ray Attenuation Property of Dendrimer-Entrapped Gold Nanoparticles. J.Phys. Chem. C 2010, 114(1), 50-56
25.   Hong Yang, Cuixia Zhang,Xiangyang Shi,* He Hu,  Xiaoxia Du, Yong Fang, Yanbin Ma,*Huixia Wu, Shiping Yang*. Water-soluble superparamagnetic manganese ferrite nanoparticles for magnetic resonance imaging. Biomaterials 2010, 31, 3667-3673
26.   Hong Yang, Yeming Zhuang, He Hu, Xiaoxia Du, Cuixia Zhang, Xiangyang Shi,*Huixia Wu, and Shiping Yang*. Silica-Coated Manganese Oxide Nanoparticles as a Platform for Targeted Magnetic Resonance and Fluorescence Imaging of Cancer Cells.Adv. Funct. Mater. 2010, 20, 1733-1741
27.   Xiangyang Shi*, Inhan Lee, Xisui Chen, Mingwu Shen, Shili Xiao, Meifang Zhu, and James R. Baker, Jr., Su He Wang*. Influence of dendrimer surface charge on the bioactivity of 2-methoxyestradiol complexed with dendrimers.Soft Matter 2010, 6, 2539-2545
28.   Shili Xiao, Mingwu Shen, Rui Guo, Qingguo Huang, Shanyuan Wang, Xiangyang Shi*. Fabrication of Multiwalled Carbon Nanotube-Reinforced Electrospun Polymer Nanofibers Containing Zero-Valent Iron Nanoparticles for Environmental Applications. J. Mater. Chem. 2010, 20, 5700-5708
29.   Mingwu Shen and Xiangyang Shi*. Dendrimer-based organic/inorganic hybrid nanoparticles in biomedical applications. Nanoscale 2010, 2, 1596-1610
30.   Ruiling Qi, Rui Guo, Mingwu Shen, Xueyan Cao, Leqiang Zhang, Jiajia Xu, Jianyong Yu, Xiangyang Shi*. Electrospun Poly(lactic-co-glycolic acid)/Halloysite Nanotube Composite Nanofibers for Drug Encapsulation and Sustained Release. J. Mater. Chem. 2010, 20, 10622-10629
31.   Han Wang, Linfeng Zheng, Chen Peng, Rui Guo, Mingwu Shen, Xiangyang Shi*, Guixiang Zhang*. Computed Tomography Imaging Of Cancer Cells Using Acetylated Dendrimer-Entrapped Gold Nanoparticles. Biomaterials 2011, 32, 2979-2988
32.   Yin Wang, Rui Guo, Xueyan Cao, Mingwu Shen, and Xiangyang Shi Encapsulation of 2-methoxyestradiol within multifunctional poly(amidoamine) dendrimers for targeted cancer therapy. Biomaterials 2011, 32, 3322-3329
33.   Xu Fang,Hui Ma, Shili Xiao,Mingwu Shen,Rui Guo,Xueyan Cao,and Xiangyang Shi*.Facile Immobilization of Gold Nanoparticles into Electrospun Polyethyleneimine/Polyvinyl Alcohol Nanofibers for Catalytic Applications. J. Mater. Chem. 2011, 21 (12), 4493-4501
34.   Rui Guo, Han Wang, Chen Peng, Mingwu Shen, Guixiang Zhang,* Xiangyang Shi*. Enhanced X-Ray Attenuation Property of Dendrimer-Entrapped Gold Nanoparticles Complexed with Diatrizoic Acid. J. Mater. Chem. 2011, 21 (13), 5120-5127
35.   Xueyan Cao, Jingjing Chen, Shihui Wen, Chen Peng, Mingwu Shen, and Xiangyang Shi*. Effect of Surface Charge of Polyethyleneimine-Modified Multiwalled Carbon Nanotubes on the Improvement of Polymerase Chain Reaction. Nanoscale 2011, 3 (4), 1741-1747.
36.   Hong Yang, Yeming Zhuang, Yun Sun, Antao Dai, Xiangyang Shi,* Dongmei Wu, Fuyou Li, He Hu and Shiping Yang*. Targeted Dual Contrast T1- and T2-weighted Magnetic Resonance Imaging of Tumors using Multifunctional Gadolinium-Labeled Superparamagnetic Iron Oxide Nanoparticles. Biomaterials 2011,32, 4584-4593
37.   Yulin Li*, Dina Maciel, Helena Tomás, João Rodrigues, Hui Ma, Xiangyang Shi. pH Sensitive laponite/alginate hybrid hydrogels: swelling behavior and release mechanism. Soft Matter 2011, 7(13), 6231-6238

 

國際交流與合作:

 

 

 

 

 

 

美國密歇根大學(University of Michigan Ann Arbor),美國加州州立大學(California State University, Los Angeles, 美國喬治亞大學格里芬分校(University of Georgia, Griffin, 美國麻省大學艾姆赫斯特分校(University of Massachusetts Amherst),德國馬普膠體與界面研究所(Max-Planck Institute of Colloids and Interfaces, 葡萄牙馬德拉大學 (Universidade da Madeira), 匈牙利徳布勒森大學(University of Debrecen)。

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