[JOC] Hydrogen Bond-Assisted 6π-Azaelectrocyclization of Penta-2,4-dienamides: Synthesis of Dihydropyridin-2(3H)-ones
writer：Xu Liu, Ning Zhang, Jiming Yang, Yongjiu Liang, Rui Zhang, and Dewen Dong
keywords：electrocyclization, dihydropyridin
source：期刊
specific source：J. Org. Chem.
Issue time：2013年
A facile and efficient synthesis of substituted dihydropyridin-2(3H)-ones is developed from penta-2,4-dienamides, in which an intramolecular C–N bond was formed through thermal 6π-azaelectrocyclization. The intramolecular hydrogen bonding-assisted cyclization reaction opens access to a variety of dihydropyridin-2(3H)-ones.